Luis Guillén is a 25-year-old professional football player from PAR. He currently plays for General Caballero JLM, wearing the number 1 shirt. He plays primarily as a Goalkeeper. He stands at 195cm tall and weighs 87kg. His preferred foot is Right.

His most recent move was a Transfer from General Caballero JLM to Club 12 de Octubre de Itauguá on 2026-07-31.

In the Paraguayan Primera Division 2025, Luis Guillén played 44 matches, averaging 0 interceptions, 0 tackles, and 0.5 clearances per game.