He currently plays for Partizan Belgrade, wearing the number 40 shirt. At the international level, he represents Serbia. He plays primarily as a Defender. His preferred foot is Both. His current market value is estimated at 6M €.

His most recent move was a from Partizan Belgrade U19 to Partizan Belgrade on 2024-12-31.

Throughout the Serbian Mozzart Bet Superliga 2025-2026, Nikola Simić featured in 25 matches, averaging 0.9 tackles, 0.9 interceptions, and 3.4 clearances per game, while blocking 0.1 shots per game.